GROW MORE INSTITUTE OF NURSING, HIMMATNAGAR
BIOCHEMISTRY

Placement – First Year	Time Allotted: Theory – 60 Hrs.

Course Description:

The course is designed to assist the students to acquire knowledge of the normal biochemical composition and functioning of human body and understand the alterations in biochemistry in diseases for practice of nursing.

Unit		Time		Content		
		(Hrs)				
			Introduction		
			Definition and significance in nursing		
I		3		Review of structure, Composition and functions of cell		
			Prokaryote and Eukaryote cell organization		
				Microscopy		
					
			Structure and functions of cell members		
			Fluid mosaic model tight junction, Cytoskeleton		
II		6		Transport mechanism: diffusion, osmosis, filtration, active channel, sodium pump		
			Acid base balance – maintenance & diagnostic tests		
				PH buffer		
					
			Composition and metabolism of Carbohydrates		
			Types, structure, composition and use		
				Monosaccharide,		
			Disaccharides,		
			Polysaccharides		
			Oligosaccharides		
				Metabolism		
III		6		Pathways of glucose:		
			Glycolysis		
			Gluconeogenesis: Cori’s cycle, Tricarboxylic acid (TCA) cycle		
			Glycogenolysis		
			Pentose phosphate pathways (Hexose mono phosphate)		
			Regulation of blood glucose level		
			Investigations and their interpretations		
						
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						Composition and metabolism of Carbohydrates			
						Types, structure, composition and uses of fatty acids			
						Nomenclature, Roles and Prostaglandins			
						Metabolism of fatty acid			
							Breakdown			
	IV		4			Synthesis			
						Metabolism of triacylglycerols			
										
							Cholesterol metabolism			
						Biosynthesis and its Regulation			
						Bile salts and bilirubin			
							Vitamin D			
							Steroid hormones			
									
						Composition and metabolism of Amino acids and Proteins			
						Types, structure, composition and uses of Amino acids and Proteins			
						Metabolism of Amino acids and Proteins			
						Protein synthesis, targeting and giycosylation			
							Chromatography graphy			
							Electrophoresis			
							Sequencing			
							Metabolism of Nitrogen			
	V			6			Fixation and Assimilation			
							Urea Cycle			
										
							Hemes and chlorophylls			
						Enzymes and co- enzymes			
							Classification			
							Properties			
							Absorption			
							Storage & transportation			
							Normal concentration			
						Investigations and their interpretations			
									
						Composition of Vitamins and minerals			
	VI		2			Vitamins and minerals :			
							Structure			
										
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			Classification	
			Properties	
			Absorption	
			Storage & transportation	
			Normal concentration	
		Investigations and their interpretations	
			
		Immunochemistry	
			Immune response,	
		Structure and classification of immunoglobins	
		Mechanism of antibody production	
VII	3		Antigens : HLA typing	
		Free radical and Antioxidants	
			Specialised Protein: Collagen, Elastin, Keratin, Myosin, Lens Protein.	
		Electrophoretic and Quantitative determination of immunoglobins – ELISA etc.	
		Investigations and their interpretations	

	 

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